Glucosamine + Chondroitin + MSM combination provides efficacious quantities of glucosamine sulfate; chondroitin sulfate; and MSM combined with vitamin C and manganese for optimizing joint health.* Glucosamine and chondroitin sulfate are essential components of joint tissue involved in the production of hyaluronic acid; which is an important component of the synovial fluid that lubricates the joints; and a major component of the connective tissue in the skin.* Methylsulfonylmethane (MSM) is an organic source of sulfur; an antioxidant mineral and critical component of structural body tissues such as cartilage. The sulfur from MSM is incorporated into joint tissues as glycosaminoglycans (or mucopolysaccharides) such as chondroitin sulfate and hyaluronic acid.* Vitamin C and manganese are required for the synthesis of collagen and cartilage.* Jarrow FORMULAS Glucosamine + Chondroitin + MSM Combination is Joint Sustain nutrition; providing a SODIUM FREE form of GS stabilized with only potassium chloride (KCl). For best results; use with Jarrow FORMULAS JarroSil ; the biologically Activated Silicon . Keep out of the reach of children.